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QUICKI Calculator

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Calculate the Quantitative Insulin Sensitivity Check Index (QUICKI) from fasting glucose and insulin to estimate insulin sensitivity, with reference bands.

Fasting Glucose
mg/dL
50300
Fasting Insulin
µIU/mL
150

QUICKI applies a logarithmic transform to fasting glucose and insulin, which tends to be more stable across a wider range of values than HOMA-IR.

QUICKI

0

Category

For informational purposes only. QUICKI is a research and screening index — confirm any concerns with a healthcare provider.

What is a QUICKI?

A QUICKI Calculator estimates insulin sensitivity using the Quantitative Insulin Sensitivity Check Index, a formula developed by Katz et al. and published in 2000 that applies logarithmic transformations to fasting glucose and fasting insulin. Unlike simpler ratio-based formulas, QUICKI's logarithmic approach is designed to produce a value that correlates more consistently with directly measured insulin sensitivity across a wide range of glucose and insulin levels.

This calculator applies the standard QUICKI formula and maps the result to general reference categories describing insulin sensitivity. It complements the HOMA-IR Calculator, which uses the same two lab values but measures insulin resistance rather than sensitivity, moving in the opposite mathematical direction.

How to use this QUICKI calculator

  1. Obtain your Fasting Glucose value in mg/dL from a fasting blood test (typically after at least 8 hours without food).
  2. Obtain your Fasting Insulin value in µIU/mL from the same fasting blood draw.
  3. Enter the Fasting Glucose value into the calculator.
  4. Enter the Fasting Insulin value into the calculator.
  5. Review the QUICKI result and its Insulin Sensitivity Category, and discuss the result with a healthcare provider for personalized interpretation.

Formula & Methodology

QUICKI = 1 ÷ [log10(Fasting Insulin, µIU/mL) + log10(Fasting Glucose, mg/dL)]

This is the original Katz et al. formula (Journal of Clinical Endocrinology & Metabolism, 2000). Commonly cited reference bands: 0.35 or above suggests normal insulin sensitivity, 0.30-0.349 suggests reduced insulin sensitivity, and below 0.30 suggests an insulin resistant range.

Worked example: for a fasting glucose of 90 mg/dL and fasting insulin of 10 µIU/mL:
- log10(10) = 1.000, log10(90) = 1.954
- QUICKI = 1 ÷ (1.000 + 1.954) = 1 ÷ 2.954 = 0.339
- A QUICKI of 0.339 falls in the Reduced insulin sensitivity range (0.30-0.349).

Frequently Asked Questions

QUICKI, the Quantitative Insulin Sensitivity Check Index, is a formula that estimates insulin sensitivity from fasting glucose and fasting insulin using a logarithmic transformation. It was developed by Katz et al. and published in the Journal of Clinical Endocrinology & Metabolism in 2000 as an alternative to HOMA-IR.
QUICKI is calculated as 1 divided by the sum of the base-10 logarithm of fasting insulin (in µIU/mL) and the base-10 logarithm of fasting glucose (in mg/dL). The logarithmic transformation is designed to produce a more linear, stable relationship with directly measured insulin sensitivity than untransformed values.
Healthy adults with normal insulin sensitivity typically score in the range of roughly 0.35 to 0.42, while values below about 0.30 to 0.35 are commonly associated with reduced insulin sensitivity or insulin resistance. Exact cutoffs vary between studies and populations, so results should be viewed as general reference points.
Both QUICKI and the [HOMA-IR Calculator](/homa-ir-calculator/) use the same two inputs — fasting glucose and fasting insulin — but move in opposite directions: a higher QUICKI value indicates greater insulin sensitivity, while a higher HOMA-IR value indicates greater insulin resistance. QUICKI's logarithmic transformation is designed to behave more consistently across a wide range of insulin and glucose values.
Raw fasting insulin and glucose values can vary widely and non-linearly with actual insulin sensitivity, so applying a logarithmic transformation compresses that variability and produces a value that correlates more consistently with directly measured insulin sensitivity in research studies. This is the key methodological difference between QUICKI and simpler ratio-based formulas like HOMA-IR.
Yes — both glucose and insulin values must be measured from the same fasting blood draw, typically after at least 8 hours without food, since eating significantly raises both values and would distort the result. Follow your lab's specific fasting instructions.
No — QUICKI is a research and screening index, not a standalone diagnostic test. Any concerns about insulin resistance or diabetes risk should be evaluated by a qualified healthcare provider using your full clinical picture and validated diagnostic criteria.
Some research suggests QUICKI correlates somewhat more consistently with gold-standard insulin sensitivity measurements (like the euglycemic clamp technique) across a broader range of values, but both are widely used surrogate indices with known limitations. Neither replaces direct insulin sensitivity testing when clinically needed.
QUICKI reflects insulin sensitivity from a single fasting measurement, while the [A1c Calculator](/a1c-calculator/) and [Estimated Average Glucose Calculator](/estimated-average-glucose-calculator/) reflect average glucose control over a longer period. Together they offer complementary views of glucose metabolism rather than measuring the same thing.
Factors commonly associated with improved insulin sensitivity in research include regular physical activity, weight management, improved sleep quality, and dietary changes such as reducing refined carbohydrate intake. Any changes aimed at improving insulin sensitivity should be made in consultation with a healthcare provider.
Also known as
quantitative insulin sensitivity check indexQUICKI formulainsulin sensitivity calculatorQUICKI indexinsulin sensitivity index